Functional connectivity changes show similar trajectories in autosomal dominant and sporadic Alzheimer disease
نویسندگان
چکیده
منابع مشابه
Impaired default network functional connectivity in autosomal dominant Alzheimer disease.
OBJECTIVE To investigate default mode network (DMN) functional connectivity MRI (fcMRI) in a large cross-sectional cohort of subjects from families harboring pathogenic presenilin-1 (PSEN1), presenilin-2 (PSEN2), and amyloid precursor protein (APP) mutations participating in the Dominantly Inherited Alzheimer Network. METHODS Eighty-three mutation carriers and 37 asymptomatic noncarriers from...
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ژورنال
عنوان ژورنال: Nature Reviews Neurology
سال: 2014
ISSN: 1759-4758,1759-4766
DOI: 10.1038/nrneurol.2014.149